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Sunday sees the initial Wear-Tyne derby since 2024, but which side will celebrate – the Black Cats or the Magpies?
"For most of last season, it was unthinkable the Wearside club getting promoted and being competitive with Eddie Howe's Newcastle, much less being above them in the table," stated football expert Chris Sutton.
"It is very different now, and the way they play makes me think they've got a genuine opportunity."
He is offering scoreline guesses for all 380 Premier League games this season, against artificial intelligence, the public and a assortment of guests.
For week 16, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the England's esports team – the Football Association's recognised esports team – at the football simulation Uefa eEuro 2025 finals tournament, which will occur at Twickenham Stadium on Saturday.
You can watch Uefa's YouTube, Instagram Live and TikTok channels, as well as the official Twitch channel and its YouTube counterpart and England's Twitch.
What are your thoughts with their scores? You can make your own predictions below.
The most popular scoreline selected for each game is displayed on the scoreboards at the foot of this page.
Predicting the right outcome (picking a win, draw or defeat) is worth 10 points. The exact score earns 40 points.
Ray, who competes for Gen City and Manchester City as well as England, is making his debut at the eEuros finals after passing the qualifying.
Eight players will play for their countries at the finals in a knockout format, vying for a six-figure prize fund and a coveted spot in the world finals play-offs, with the Danish representative Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray said. "I have a really good coach by my side and training has been going well.
"It's always an honour to play for your country. Obviously when you are younger, you imagine doing it as an professional footballer, but when you pursue a career in this profession and there is an chance to represent England, wearing the Three Lions is something incredible.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him throughout the year just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"For me he is the best player in the world so defeating him in a tournament like this just gives you a crazy boost of confidence."
Premier League Forecasts
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were excellent against Arsenal at the end of November, when they secured a point after being reduced to 10 men, and many thought they've turned a corner, they could potentially be challengers for the crown.
In the matches following, however, they were overpowered by Leeds, looked lethargic against Bournemouth and this week got defeated by Atalanta in the Champions League.
So boss Enzo Maresca desperately requires a win here to return to winning ways, but it will be a challenge because Everton are such a potent team.
Two of their stars are playing exceptionally and they have got a bit of form at the moment.
Current evidence suggests you would probably back Everton, while the most prudent prediction would probably be a draw, but I'm throwing caution to the wind.
The Blues have failed to given me any good cause to back them recently, but I just have a feeling they will win this match because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be fascinating to see what we get from Liverpool.
I am really pleased for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the controversy with Mohamed Salah this week.
Slot should not have to put up with that drama. I know Salah has been a icon for the club but fundamentally Slot just wants to win games and there is no bias in his team selection.
Liverpool changed their formation against Inter and went with a midfield diamond formation and two up top.
Everyone is going to be talking about whether Salah is back for this game, but the only way he is going to be reintegrated is if he apologises.
Slot's primary concern will be on winning this game, but it is a challenging encounter.
You could argue it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their efforts at the San Siro will have drained them.
I have whacked a couple of Brighton players in my Fantasy Premier League side, so they will almost certainly blank - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the benefit of a free week while Newcastle had to work so hard against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Apart from their excellent performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, particularly straight after they've played in the Champions League.
I am expecting that pattern to continue on Sunday, and their fatigue is likely to be a significant issue in how this game goes because of Sunderland's energetic style.
Their match against Arsenal demonstrated how relentless Regis le Bris's side are. They overpowered the Gunners, and it was a joy to watch.
Everyone talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been excellent, but Noah Sadiki, who plays alongside him, has also been one of the signings of the season and warrants praise too.
This promises to be this being the best game|most exciting fixture